The SLC17A2 Polyclonal Antibody (PAC022624) is a cutting-edge tool for researchers studying SLC17A2, a key protein involved in ion transport and neurotransmitter uptake. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the SLC17A2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable asset for studies in neuroscience, neurology, and pharmacology.SLC17A2, also known as vesicular glutamate transporter 3 (VGLUT3), is essential for the packaging and transport of glutamate, the major excitatory neurotransmitter in the brain.
Dysfunction of SLC17A2 has been linked to neurological disorders such as Parkinson's disease, schizophrenia, and epilepsy, highlighting its critical role in maintaining proper brain function. Investigating the function and regulation of SLC17A2 is vital for advancing our understanding of these conditions and developing targeted therapeutic interventions.
Antibody Name:
SLC17A2 Antibody (PACO22624)
Antibody SKU:
PACO22624
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human SLC17A2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HepG2 cells, using SLC17A2 antibody.
Background:
May be involved in actively transporting phosphate into cells via Na+ cotransport By similarity.
SLC17A2: May be involved in actively transporting phosphate into cells via Na(+) cotransport. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family; TransporterChromosomal Location of Human Ortholog: 6p21.3Cellular Component: membrane; integral to plasma membraneMolecular Function: sodium:phosphate symporter activityBiological Process: sodium ion transport; phosphate metabolic process
solute carrier family 17 (sodium phosphate), member 2
NCBI Official Symbol:
SLC17A2Â Â
NCBI Official Synonym Symbols:
NPT3Â Â
NCBI Protein Information:
sodium-dependent phosphate transport protein 3; Na(+)/PI cotransporter 3; sodium phosphate transporter 3; sodium/phosphate cotransporter 3; solute carrier family 17 member 2; solute carrier family 17 (vesicular glutamate transporter), member 2
UniProt Protein Name:
Sodium-dependent phosphate transport protein 3
UniProt Synonym Protein Names:
Na(+)/PI cotransporter 3; Sodium/phosphate cotransporter 3; Solute carrier family 17 member 2
