The SLC1A6 Antibody (CAB2904) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for use in Western blot applications.SLC1A6, also known as excitatory amino acid transporter 4 (EAAT4), is crucial for maintaining proper excitatory neurotransmission by facilitating the uptake of glutamate in the brain. Dysregulation of SLC1A6 has been implicated in various neurological disorders, including epilepsy, Alzheimer's disease, and schizophrenia.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
SLC1A6 Antibody
SKU:
CAB2904
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
EAAT4, SLC1A6
Positive Sample:
U-251MG, HepG2, A375, Mouse liver
Cellular Localization:
Membrane, Multi-Pass Membrane Protein.
Calculated MW:
62kDa
Observed MW:
64kDa
Predicted to enable high-affinity glutamate transmembrane transporter activity. Involved in neurotransmitter uptake. Located in intermediate filament cytoskeleton and plasma membrane.
Purification Method
Affinity purification
Gene ID
6511
RRID
AB_2764724
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SLC1A6 Rabbit pAb (CAB2904) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
