The SLC22A11 Antibody (CAB7816) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SLC22A11 protein, this antibody enables the accurate detection and analysis of SLC22A11 in various cell types, making it an ideal choice for studies in pharmacology and drug transport research.SLC22A11, also known as organic cation transporter 4, plays a crucial role in the uptake and excretion of a wide range of drugs and endogenous compounds in the body.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SLC22A11 Antibody
SKU:
CAB7816
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
OAT4, hOAT4, SLC22A11
Positive Sample:
MDA-MB-231, HepG2
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
60kDa
Observed MW:
65kDa
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
55867
RRID
AB_2772248
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SLC22A11 Rabbit pAb (CAB7816) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.