The SLC29A3 Antibody (CAB10377) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the SLC29A3 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential component for studies in molecular biology and pharmacology.SLC29A3, also known as hENT3, plays a crucial role in nucleoside and nucleobase transport, which is essential for processes such as DNA replication and RNA synthesis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
SLC29A3 Antibody
SKU:
CAB10377
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ENT3, HJCD, PHID, HCLAP, SLC29A3
Positive Sample:
HeLa, SKOV3, HT-29, 293T, A-549
Cellular Localization:
Late Endosome Membrane, Lysosome Membrane, Membrane, Multi-Pass Membrane Protein.
Calculated MW:
52kDa
Observed MW:
50kDa
This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.
Purification Method
Affinity purification
Gene ID
55315
RRID
AB_2757924
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SLC29A3 Rabbit pAb (CAB10377) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
