The SLC30A9 Polyclonal Antibody (PAC022698) is a valuable tool for researchers studying SLC30A9, a member of the SLC30 family of zinc transporters that plays a crucial role in cellular zinc homeostasis. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.SLC30A9 is known to be involved in the transport of zinc ions across cellular membranes, which has implications for various physiological processes such as immune function, neuronal development, and insulin secretion. Dysregulation of SLC30A9 has been linked to diseases like diabetes, Alzheimer's, and cancer, making it an attractive target for further investigation.
By using the SLC30A9 Polyclonal Antibody, researchers can accurately detect and analyze SLC30A9 protein levels in different cell types, allowing for a better understanding of its role in health and disease. This antibody is a valuable tool for studies in biochemistry, molecular biology, and cell biology, and has the potential to contribute to the development of novel therapeutic strategies targeting SLC30A9-dependent pathways.
Antibody Name:
SLC30A9 Antibody (PACO22698)
Antibody SKU:
PACO22698
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human SLC30A9.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HepG2 cells, using SLC30A9 antibody.
Background:
Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors By similarity. Plays a role in transcriptional activation of Wnt-responsive genes By similarity.
Synonyms:
Zinc transporter 9ZnT-9; Solute carrier family 30 member 9; Human embryonic lung protein; HUEL SLC30A9;
UniProt Protein Function:
SLC30A9: Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors. Plays a role in transcriptional activation of Wnt- responsive genes. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.Protein type: Nuclear receptor co-regulator; Membrane protein, multi-pass; Transporter; Transporter, SLC family; Motility/polarity/chemotaxis; Cytoskeletal; Membrane protein, integralChromosomal Location of Human Ortholog: 4p13Cellular Component: cytoskeleton; integral to membrane; nucleusMolecular Function: ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; cation transmembrane transporter activity; chromatin binding; transcription factor activityBiological Process: transcription, DNA-dependent; nucleotide-excision repair; positive regulation of transcription from RNA polymerase II promoter; zinc ion transport
solute carrier family 30 (zinc transporter), member 9
NCBI Official Symbol:
SLC30A9Â Â
NCBI Official Synonym Symbols:
HUEL; ZNT9; GAC63; C4orf1Â Â
NCBI Protein Information:
zinc transporter 9; znT-9; human embryonic lung protein; expressed in human embryonic lung; solute carrier family 30 member 9; GRIP1-dependent nuclear receptor coactivator
UniProt Protein Name:
Zinc transporter 9
UniProt Synonym Protein Names:
Human embryonic lung protein; HuEL; Solute carrier family 30 member 9
