The SLC6A7 Polyclonal Antibody (PACO20527) is a valuable tool for researchers studying the SLC6A7 protein, a member of the neurotransmitter sodium symporter family involved in the transport of neurotransmitters like GABA. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SLC6A7 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for studies in neuroscience and pharmacology.
SLC6A7 is known to play a crucial role in the regulation of GABA neurotransmission, making it a potential target for research on neurological disorders, including epilepsy, anxiety, and depression. By understanding the function and regulation of SLC6A7, researchers can gain insight into the mechanisms underlying these conditions and potentially identify new therapeutic approaches. The SLC6A7 Polyclonal Antibody is a valuable tool for exploring the role of SLC6A7 in neurotransmitter transport and neurological function.
Antibody Name:
SLC6A7 Antibody (PACO20527)
Antibody SKU:
PACO20527
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Rat
Immunogen:
Synthetic peptide of human SLC6A7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20527(SLC6A7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20527(SLC6A7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene is a member of the gamma-aminobutyric acid, (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements.
Synonyms:
solute carrier family 6 (neurotransmitter transporter), member 7
UniProt Protein Function:
Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals.
UniProt Protein Details:
NCBI Summary:
This gene is a member of the gamma-aminobutyric acid (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements. [provided by RefSeq, Jul 2008]
