The SLC9A7 Polyclonal Antibody (PACO05534) is a valuable tool for researchers studying SLC9A7, a protein involved in ion transport and cellular homeostasis. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in Western blot applications. By targeting the SLC9A7 protein, this antibody allows for precise detection and analysis in various cell types, making it an ideal choice for studies in cell biology and disease mechanisms.SLC9A7, also known as sodium/hydrogen exchanger 7, plays a crucial role in maintaining cellular pH and ion balance, essential for proper cell function and survival.
Dysregulation of SLC9A7 has been implicated in various pathological conditions, including cancer, neurological disorders, and cardiovascular diseases. Therefore, investigating the function and regulation of SLC9A7 using this antibody can provide valuable insights into disease mechanisms and potential therapeutic targets.Overall, the SLC9A7 Polyclonal Antibody (PACO05534) is a reliable tool for researchers aiming to understand the role of SLC9A7 in cellular physiology and disease pathology, paving the way for advancements in drug development and personalized medicine strategies.
Antibody Name:
SLC9A7 Antibody (PACO05534)
Antibody SKU:
PACO05534
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from the C-terminal region of human NHE-7.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
SLC9A7; NHE7; Sodium/hydrogen exchanger 7; Na(+)/H(+) exchanger 7; NHE-7; Solute carrier family 9 member 7
UniProt Protein Function:
SOX8: May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 16p13.3Cellular Component: cytoplasm; nucleusMolecular Function: DNA binding; protein heterodimerization activity; transcription factor bindingBiological Process: negative regulation of photoreceptor cell differentiation; transcription from RNA polymerase II promoter; fat cell differentiation; cell fate commitment; positive regulation of gliogenesis; in utero embryonic development; astrocyte fate commitment; positive regulation of transcription, DNA-dependent; male gonad development; cell maturation; signal transduction; Sertoli cell development; enteric nervous system development; peripheral nervous system development; osteoblast differentiation; retina development in camera-type eye; positive regulation of osteoblast proliferation; oligodendrocyte differentiation; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of myoblast differentiation; neural crest cell migration; negative regulation of apoptosis
UniProt Protein Details:
NCBI Summary:
This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
