The SNRPB2 Antibody (CAB8908) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting SNRPB2 in human samples, making it ideal for use in Western blot applications.SNRPB2 is a core component of the spliceosome, a complex molecular machine responsible for removing introns from pre-mRNA to generate mature mRNA. Dysregulation of SNRPB2 has been linked to various diseases, including cancer and neurological disorders, highlighting its importance in cellular processes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SNRPB2 Antibody
SKU:
CAB8908
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
Msl1, U2B'', SNRPB2
Positive Sample:
HeLa, U-87MG, HT-1080, LO2, 293T, Mouse liver
Cellular Localization:
Nucleus.
Calculated MW:
25kDa
Observed MW:
30kDa
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene.
Purification Method
Affinity purification
Gene ID
6629
RRID
AB_2772327
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SNRPB2 Rabbit pAb (CAB8908) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
