The SNX20 Polyclonal Antibody (PACO12380) is a valuable tool for researchers studying SNX20, a key protein involved in intracellular membrane trafficking and endosomal sorting. This antibody, produced in rabbits, shows high specificity and sensitivity for detecting SNX20 in a variety of samples, making it an essential component for experiments involving cell biology and signal transduction studies.SNX20 is known to play a critical role in the regulation of endosomal trafficking pathways, particularly in the sorting of endocytosed cargo proteins. Its function in maintaining cellular homeostasis and organelle dynamics makes it a significant target for research in areas such as membrane dynamics, protein trafficking, and organelle biogenesis.
The SNX20 Polyclonal Antibody enables researchers to investigate the role of SNX20 in these processes, leading to a better understanding of cellular functions and potential therapeutic targets for various diseases.Overall, the SNX20 Polyclonal Antibody (PACO12380) is a reliable tool for scientists looking to study SNX20 and its involvement in intracellular trafficking pathways. Its high reactivity and specificity make it an ideal choice for experiments aimed at unraveling the intricate mechanisms of cellular transport and organelle dynamics.
SNX20: Serves as a sorting protein that cycles P-selectin glycoprotein ligand 1 (PSLG1) into endosomes with no impact on leukocytes recruitment. Belongs to the sorting nexin family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Lipid-bindingChromosomal Location of Human Ortholog: 16q12.1Cellular Component: plasma membrane; endosome membrane; nucleusMolecular Function: protein binding; phosphoinositide bindingBiological Process: protein transport
UniProt Protein Details:
NCBI Summary:
SNX20 interacts with the cytoplasmic domain of PSGL1 (SELPLG; MIM 600738) and cycles PSGL1 into endosomes.[supplied by OMIM, Feb 2010]
