The SOAT1 Monoclonal Antibody (CAB23284) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from mouse hybridomas, is highly specific to human SOAT1 and has been validated for use in various applications, including immunofluorescence and flow cytometry.SOAT1, also known as acyl-coenzyme A:cholesterol acyltransferase 1, plays a crucial role in the regulation of cholesterol levels in cells by esterifying excess cholesterol into cholesterol esters for storage. Dysregulation of SOAT1 has been implicated in various diseases, including atherosclerosis, Alzheimer's disease, and obesity.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
SOAT1 Monoclonal Antibody
SKU:
CAB23284
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC59877
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene.
Purification Method
Affinity purification
Gene ID
6646
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SOAT1 Rabbit mAb (CAB23284) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): HT-29 Exposure time: 30s.
