The SOX18 Antibody (CAB16536) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high specificity for SOX18 and is suitable for Western blot applications in human samples.SOX18 is a transcription factor that regulates gene expression, contributing to the formation of blood and lymphatic vessels during development. Dysregulation of SOX18 has been linked to various diseases, including cardiovascular disorders and certain types of cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
SOX18 Antibody
SKU:
CAB16536
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HLTS, HLTRS, SOX18
Positive Sample:
Mouse lung, Rat kidney
Cellular Localization:
Nucleus.
Calculated MW:
41kDa
Observed MW:
Refertofigures
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.
Purification Method
Affinity purification
Gene ID
54345
RRID
AB_2772353
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SOX18 Rabbit pAb (CAB16536) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
