The SpanXe Polyclonal Antibody (PACO12419) is a versatile tool for researchers studying the SpanXe protein, a crucial player in cancer biology. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the SpanXe protein, this antibody enables the detection and analysis of SpanXe in various cell types, making it an excellent choice for studies in cancer research.SpanXe, a member of the cancer-testis antigen family, is known for its aberrant expression in cancer cells, making it a potential target for cancer therapy and diagnostic biomarkers.
Its involvement in tumorigenesis and metastasis highlights its importance in cancer progression, making it a promising avenue for further investigation. By utilizing the SpanXe Polyclonal Antibody, researchers can gain valuable insights into the role of SpanXe in cancer development and potentially identify new therapeutic strategies for combating this disease.
SPANX family, member E;SPANXE;MGC71908;SPANX-A2;SPANX-C;SPANX-D;SPANXA2;SPANXD ;
UniProt Protein Function:
SPANXC: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008]Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xq27.1Cellular Component: cytoplasm; nucleus
UniProt Protein Details:
NCBI Summary:
Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008]
