The SPATA6 Monoclonal Antibody (PAC015160) is a valuable tool for researchers studying SPATA6, a protein involved in spermatogenesis and male fertility. This antibody, generated in mice, is highly specific to human samples and is suitable for use in Western blot and immunohistochemistry applications. It binds specifically to SPATA6, allowing for the detection and analysis of this protein in various tissues and cell types.
SPATA6 is a key player in the process of sperm production and has been linked to male infertility in some studies. Understanding the function and regulation of SPATA6 is essential for advancements in reproductive biology and potential treatments for male infertility. This antibody provides researchers with a reliable tool for investigating the role of SPATA6 in spermatogenesis and fertility-related disorders.
Antibody Name:
SPATA6 Antibody (PACO15160)
Antibody SKU:
PACO15160
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human SPATA6
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO15160(SPATA6 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15160(SPATA6 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The Spata6 gene consists of 15 exons ranging in size between 40 and 596 bp. It may play a role in spermatid maturation or sperm function. The Spata6 gene was localized to chromosome 5, region q34-35 in the rat and to chromosome 1, region p32-35 in the human.
Synonyms:
spermatogenesis associated 6
UniProt Protein Function:
SPATA6: May play a role in spermatid maturation or sperm function. Belongs to the SPATA6 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 1p33Cellular Component: extracellular regionBiological Process: multicellular organismal development; spermatogenesis; cell differentiation
