The SPSB1 Antibody (CAB13886) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high specificity and sensitivity towards SPSB1 in human samples, making it suitable for use in Western blot applications.SPSB1, also known as SPRY domain-containing SOCS box protein 1, is known to interact with multiple signaling molecules and enzymes, influencing cellular pathways related to growth, differentiation, and immune response. Its role in regulating protein turnover and signal transduction pathways makes it a potential target for therapeutic interventions in diseases like cancer and inflammatory disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SPSB1 Antibody
SKU:
CAB13886
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SSB1, SSB-1, SPSB1
Positive Sample:
U-87MG, A-549, A375, Mouse spleen, Rat testis
Cellular Localization:
Cytoplasm.
Calculated MW:
31kDa
Observed MW:
31kDa
Enables ubiquitin ligase-substrate adaptor activity. Involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Located in cytosol.
Purification Method
Affinity purification
Gene ID
80176
RRID
AB_2760739
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SPSB1 Rabbit pAb (CAB13886) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.