The SPTLC2 Antibody (CAB11716) is a high-quality antibody developed for reliable detection and analysis of target proteins. SPTLC2 is a key enzyme involved in sphingolipid biosynthesis, with implications in various cellular processes such as cell growth, differentiation, and apoptosis.This polyclonal antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for a wide range of applications including Western blotting, immunofluorescence, and immunohistochemistry. By specifically binding to SPTLC2, researchers can accurately detect and analyze the protein in different cell types and tissues, providing valuable insights into its biological functions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SPTLC2 Antibody
SKU:
CAB11716
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.
Purification Method
Affinity purification
Gene ID
9517
RRID
AB_2758712
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SPTLC2 Rabbit pAb (CAB11716) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
