The SSBP3 Antibody (PAC059441) is a high-quality polyclonal antibody designed for research involving SSBP3, a protein involved in DNA replication and repair processes. This antibody, raised in rabbits, is specifically reactive with human samples and is validated for use in various applications such as Western blotting and immunofluorescence.SSBP3, also known as the single-stranded DNA-binding protein, plays a critical role in maintaining genomic stability by binding to single-stranded DNA regions and facilitating DNA replication and repair processes. Its involvement in these key cellular functions makes it a valuable target for research in fields such as oncology, genetics, and molecular biology.
By utilizing the SSBP3 Antibody, researchers can detect and analyze the expression of SSBP3 in different cell types and tissues, providing valuable insights into its function and potential implications in diseases such as cancer and genetic disorders. This antibody is a powerful tool for studies aimed at understanding the molecular mechanisms underlying DNA repair and replication, contributing to the development of novel therapeutic strategies in the future.
Antibody Name:
SSBP3 Antibody (PACO59441)
Antibody SKU:
PACO59441
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:500-1:1000
Species Reactivity:
Human
Immunogen:
Recombinant Human Single-stranded DNA-binding protein 3 protein (185-321AA)
IHC image of PACO59441 diluted at 1:600 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
May be involved in transcription regulation of the α 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region.
Synonyms:
Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein), SSBP3, SSDP SSDP1
UniProt Protein Function:
SSBP3: May be involved in transcription regulation of the alpha 2(I) collagen gene where it binds to the single-stranded polypyrimidine sequences in the promoter region. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Transcription regulation; Cell cycle regulation; DNA-bindingChromosomal Location of Human Ortholog: 1p32.3Molecular Function: protein binding
