The ST18 Monoclonal Antibody (PACO01545) is a valuable tool for researchers studying the ST18 protein, a transcription factor involved in various cellular processes, including inflammation and apoptosis. This antibody, produced using hybridoma technology, shows high specificity and sensitivity towards the ST18 protein in human samples, making it suitable for applications such as Western blot and immunohistochemistry.ST18, also known as zinc finger protein 179 (ZNF179), is known to modulate gene expression and play a role in inflammatory responses and cell death pathways.
Its dysregulation has been implicated in diseases such as cancer, neurodegenerative disorders, and autoimmune conditions. By targeting ST18 with this antibody, researchers can gain insights into its function and potential therapeutic applications in these disease contexts.Overall, the ST18 Monoclonal Antibody (PACO01545) is a valuable tool for investigating the role of ST18 in various biological processes and diseases, offering researchers a reliable means of studying this important protein in their experiments.
Antibody Name:
ST18 Antibody
Antibody SKU:
PACO01545
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human ST18.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
ST18; KIAA0535; ZNF387; Suppression of tumorigenicity 18 protein; Zinc finger protein 387
UniProt Protein Function:
ST18: Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters. Inhibits colony formation in cultured breast cancer cells.Chromosomal Location of Human Ortholog: 8q11.23Cellular Component: nucleusMolecular Function: DNA binding; zinc ion binding; transcription factor activityBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
