The ST18 Polyclonal Antibody (PAC021690) is a valuable tool for researchers studying the ST18 protein, a transcription factor involved in various cellular processes, including inflammation and immunity. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples and is validated for use in Western blot applications.ST18, also known as suppression of tumorigenicity 18, has been implicated in regulating gene expression related to cell proliferation, differentiation, and apoptosis. Its dysregulation has been linked to several diseases, including cancer, inflammatory conditions, and autoimmune disorders.
The ST18 Polyclonal Antibody enables precise detection and analysis of ST18 protein levels in different cell types, making it an excellent choice for studies in immunology and cancer research.By elucidating the role of ST18 in disease pathways, researchers can potentially identify novel therapeutic targets and develop innovative treatment strategies for conditions affected by ST18 dysregulation. This antibody is a valuable tool for advancing our understanding of ST18 biology and its implications in human health.
Antibody Name:
ST18 Antibody (PACO21690)
Antibody SKU:
PACO21690
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from N-terminal of human ZNF387.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Clonality:
Polyclonal
Conjugate:
Non-conjugated
Western blot analysis of extracts from HUVEC cells, using ZNF387 antibody.
Synonyms:
Suppression of tumorigenicity protein 18; Zinc finger protein 387; ST18; KIAA0535; ZNF387
UniProt Protein Function:
ST18: Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters. Inhibits colony formation in cultured breast cancer cells.Chromosomal Location of Human Ortholog: 8q11.23Cellular Component: nucleusMolecular Function: DNA binding; zinc ion binding; transcription factor activityBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
