The STARD13 Polyclonal Antibody (PAC023298) is an essential tool for researchers studying STARD13, a protein involved in intracellular lipid transport and metabolism. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting STARD13 in human samples, making it an ideal choice for Western blot analysis.STARD13, also known as StAR-related lipid transfer protein 13, plays a critical role in cellular lipid homeostasis and may be involved in diseases related to lipid dysregulation, such as metabolic disorders and cardiovascular disease. By targeting STARD13 with this antibody, researchers can gain valuable insights into the function and regulation of this protein, providing a deeper understanding of lipid metabolism and its implications in various pathological conditions.
Whether investigating lipid transport mechanisms or exploring the role of STARD13 in disease, this polyclonal antibody is a valuable tool for any research project focused on lipid metabolism and related disorders. Its high specificity and reliability ensure accurate detection of STARD13, facilitating precise and reproducible results in a wide range of experimental settings.
Synthesized peptide derived from N-terminal of human STA13.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using STA13 antibody.
Immunofluorescence analysis of A549 cells, using STA13 antibody.
Background:
GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
Synonyms:
STA13; START domain containing 13; START domain- containing protein 13; StAR-related lipid transfer protein 13; deleted in liver cancer 2
UniProt Protein Function:
GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
