The STK32B Polyclonal Antibody (PAC020619) is specifically designed for researchers studying STK32B, a protein kinase involved in various cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It targets the STK32B protein, facilitating its detection and analysis in different cell types, making it a versatile tool for studies in cell biology and signal transduction pathways.
STK32B, also known as serine/threonine kinase 32B, is known to play a crucial role in cellular signaling, cell cycle regulation, and possibly in cancer development. Its involvement in these key pathways makes it a promising target for further investigation in cancer research and drug development. Understanding the function and regulation of STK32B may provide valuable insights into potential therapeutic strategies for cancer treatment.
Antibody Name:
STK32B Antibody (PACO20619)
Antibody SKU:
PACO20619
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human STK32B
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20619(STK32B Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO20619(STK32B Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
STK32B is a 414 amino acid, protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Using magnesium as a cofactor, YANK2 functions to catalyze the ATP-dependent phosphorylation of target proteins and may play a role in various signaling events throughout the cell. Multiple isoforms of YANK2 exist due to alternatively splicing events.
Synonyms:
serine/threonine kinase 32B
UniProt Protein Function:
Catalytic activity: ATP + a protein = ADP + a phosphoprotein.Cofactor: Magnesium By similarity.Sequence similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Contains 1 protein kinase domain.Sequence caution: The sequence AAQ88719.1 differs from that shown. Reason: Erroneous initiation.
