The STYK1 Polyclonal Antibody (PAC012569) is a valuable tool for researchers studying the STYK1 protein, a receptor tyrosine kinase involved in cancer development and progression. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the STYK1 protein, this antibody enables precise detection and analysis of STYK1 expression in various cell types, making it an essential tool for cancer research and drug development.STYK1, also known as novel tyrosine kinase 1, is a promising therapeutic target in cancer due to its role in promoting cell proliferation, survival, and metastasis.
Understanding the function of STYK1 is essential for developing targeted therapies that can effectively inhibit its oncogenic activity. The STYK1 Polyclonal Antibody provides researchers with a reliable tool to investigate the expression levels and signaling pathways associated with STYK1, facilitating advancements in cancer treatment strategies.
STYK1: Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. Belongs to the protein kinase superfamily. Tyr protein kinase family.Protein type: Protein kinase, TK; EC 2.7.10.2; Protein kinase, tyrosine (receptor); Oncoprotein; Membrane protein, integral; Kinase, protein; TK group; TK-Unique familyChromosomal Location of Human Ortholog: 12p13.2Cellular Component: extrinsic to internal side of plasma membrane; plasma membraneMolecular Function: non-membrane spanning protein tyrosine kinase activity; protein binding; receptor bindingBiological Process: cell differentiation; cell migration; innate immune response; regulation of cell proliferation; transmembrane receptor protein tyrosine kinase signaling pathway
UniProt Protein Details:
NCBI Summary:
Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008]
