The SUCNR1 Polyclonal Antibody (PACO04783) is a valuable tool for research involving SUCNR1, a cell surface receptor also known as GPR91 that plays a critical role in immune response regulation and metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.SUCNR1 is a key player in mediating the effects of succinate, a metabolite involved in cellular energy production and signaling. Activation of SUCNR1 has been linked to inflammation, immune cell activation, and metabolic regulation, making it a promising target for studies in immunology, metabolic disorders, and cancer research.
By detecting and analyzing SUCNR1 expression in different cell types, researchers can gain valuable insights into its function and potential therapeutic applications.Investigating the role of SUCNR1 in immune modulation and metabolic pathways is crucial for understanding its implications in various diseases and developing targeted therapies. The SUCNR1 Polyclonal Antibody (PACO04783) provides researchers with a reliable tool to explore the functions of this important receptor in a wide range of biological contexts.
Antibody Name:
SUCNR1 Antibody
Antibody SKU:
PACO04783
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human GPR91.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
SUCNR1: Receptor for succinate. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-passChromosomal Location of Human Ortholog: 3q25.1Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis. [provided by RefSeq, Oct 2009]
