Description
SUGP1 Antibody (PACO12139)
The SUGP1 Polyclonal Antibody (PACO12139) is a valuable tool for researchers studying SUGP1, a protein involved in mRNA splicing and processing. This antibody is produced in rabbits and is highly specific for human samples, making it ideal for use in Western blot applications. By binding to the SUGP1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential reagent for studies in molecular biology and RNA processing.SUGP1, also known as Suppressor of GFP1, plays a crucial role in the regulation of gene expression by facilitating the removal of introns from pre-mRNA molecules.
Its involvement in mRNA splicing makes it a key player in cellular processes such as protein synthesis and gene regulation. Research into the function of SUGP1 is important for understanding the molecular mechanisms that control gene expression and for exploring potential therapeutic targets for diseases related to RNA processing defects.By using the SUGP1 Polyclonal Antibody in your research, you can gain valuable insights into the role of SUGP1 in mRNA splicing and gene expression regulation, leading to a better understanding of cellular processes and potential targets for therapeutic intervention.
| Antibody Name: | SUGP1 Antibody (PACO12139) |
| Antibody SKU: | PACO12139 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human SF4 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | splicing factor 4;SF4;DKFZp434E2216;F23858;RBP ; |
| UniProt Protein Function: | SF4: Plays a role in pre-mRNA splicing. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding; RNA processing; RNA splicing Chromosomal Location of Human Ortholog: 19p13.11 Cellular Component: nucleoplasm Molecular Function:protein binding Biological Process: nuclear mRNA splicing, via spliceosome |
| NCBI Summary: | SF4 is a member of the SURP family of splicing factors.[supplied by OMIM, Sep 2003] |
| UniProt Code: | Q8IWZ8 |
| NCBI GenInfo Identifier: | 61216666 |
| NCBI Gene ID: | 57794 |
| NCBI Accession: | Q8IWZ8.2 |
| UniProt Secondary Accession: | Q8IWZ8,O60378, Q6P3X9, Q8TCQ4, Q8WWT4, Q8WWT5, Q9NTG3 |
| UniProt Related Accession: | Q8IWZ8 |
| Molecular Weight: | 24,297 Da |
| NCBI Full Name: | SURP and G-patch domain-containing protein 1 |
| NCBI Synonym Full Names: | SURP and G-patch domain containing 1 |
| NCBI Official Symbol: | SUGP1Â Â |
| NCBI Official Synonym Symbols: | RBP; SF4; F23858Â Â |
| NCBI Protein Information: | SURP and G-patch domain-containing protein 1 |
| UniProt Protein Name: | SURP and G-patch domain-containing protein 1 |
| UniProt Synonym Protein Names: | RNA-binding protein RBP; Splicing factor 4 |
| Protein Family: | SURP and G-patch domain-containing protein |
| UniProt Gene Name: | SUGP1Â Â |
| UniProt Entry Name: | SUGP1_HUMAN |