The SYCP3 Antibody (CAB9548) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through immunization of rabbits, has high specificity and sensitivity for detecting SYCP3 in human samples, making it ideal for use in Western blot applications.SYCP3 is a crucial component in the formation of the synaptonemal complex, which ensures proper alignment and pairing of homologous chromosomes during meiosis. Dysregulation of SYCP3 has been linked to meiotic defects, infertility, and genetic disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
SYCP3 Antibody
SKU:
CAB9548
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
COR1, SCP3, SPGF4, RPRGL4, SYCP3
Positive Sample:
Mouse ovary, Rat ovary
Cellular Localization:
Chromosome, Nucleus.
Calculated MW:
28kDa
Observed MW:
28kDa
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
Purification Method
Affinity purification
Gene ID
50511
RRID
AB_2772482
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SYCP3 Rabbit pAb (CAB9548) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.