The SYNJ2 Antibody (PAC012602) is a polyclonal antibody designed for research involving SYNJ2, a protein involved in membrane trafficking and cell signaling pathways. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot and immunofluorescence applications. It binds to the SYNJ2 protein, enabling detection and analysis in various cell types, making it ideal for studies in cell biology and neuroscience research.SYNJ2, also known as synaptojanin-2, is a phosphoinositide phosphatase that plays a critical role in regulating synaptic vesicle endocytosis and neurotransmitter release.
Dysregulation of SYNJ2 has been implicated in neurological disorders such as Parkinson's disease and Alzheimer's disease, making it a valuable target for research into neurodegenerative diseases. Understanding the function of SYNJ2 is essential for developing therapies that target synaptic dysfunction in these conditions.Overall, the SYNJ2 Antibody (PAC012602) is a valuable tool for researchers studying membrane trafficking, cell signaling, and neurodegenerative diseases. Its specificity and effectiveness in detecting SYNJ2 make it a reliable choice for immunological studies in various research fields.
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
