Description
TACC1 Antibody (PACO12618)
The TACC1 Polyclonal Antibody (PACO12618) is a valuable tool for researchers studying TACC1, a protein involved in cell division and microtubule organization. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the TACC1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and cancer research.
TACC1 plays a crucial role in regulating spindle assembly and chromosome segregation during cell division, making it a key player in maintaining genomic stability. Dysregulation of TACC1 has been implicated in various types of cancer, highlighting its potential as a therapeutic target for cancer treatment. By studying the function and expression of TACC1, researchers aim to uncover new insights into tumor biology and identify potential targets for cancer therapy.
| Antibody Name: | TACC1 Antibody (PACO12618) |
| Antibody SKU: | PACO12618 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human TACC1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | transforming, acid, c coiled-coil containing protein 1;TACC1;DKFZp686K18126;FLJ42304;Ga55;KIAA1103 ; |
| UniProt Protein Function: | TACC1: Likely involved in the processes that promote cell division prior to the formation of differentiated tissues. Belongs to the TACC family. 8 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Cell development/differentiation Chromosomal Location of Human Ortholog: 8p11.22 Cellular Component: cytoplasm; intermediate filament cytoskeleton; microtubule cytoskeleton Molecular Function:protein binding Biological Process: cell proliferation; cerebral cortex development; microtubule cytoskeleton organization and biogenesis |
| NCBI Summary: | This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009] |
| UniProt Code: | O75410 |
| NCBI GenInfo Identifier: | 59800391 |
| NCBI Gene ID: | 6867 |
| NCBI Accession: | O75410.2 |
| UniProt Secondary Accession: | O75410,Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2 Q8NEY7, Q9UPP9, B2RBD9, D3DSX6, |
| UniProt Related Accession: | O75410 |
| Molecular Weight: | 17,815 Da |
| NCBI Full Name: | Transforming acidic coiled-coil-containing protein 1 |
| NCBI Synonym Full Names: | transforming acidic coiled-coil containing protein 1 |
| NCBI Official Symbol: | TACC1Â Â |
| NCBI Official Synonym Symbols: | Ga55Â Â |
| NCBI Protein Information: | transforming acidic coiled-coil-containing protein 1 |
| UniProt Protein Name: | Transforming acidic coiled-coil-containing protein 1 |
| UniProt Synonym Protein Names: | Gastric cancer antigen Ga55; Taxin-1 |
| Protein Family: | Transforming acidic coiled-coil-containing protein |
| UniProt Gene Name: | TACC1Â Â |
| UniProt Entry Name: | TACC1_HUMAN |
