The TAS2R20 Antibody (PACO03802) is a polyclonal antibody designed for research involving TAS2R20, a taste receptor protein involved in bitter taste perception. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting. By binding to the TAS2R20 protein, researchers are able to detect and analyze its presence in different cell types, making it an ideal tool for studies in taste perception and sensory biology.TAS2R20 is a member of the taste receptor family and plays a crucial role in detecting bitter compounds, which can affect food preferences and overall dietary choices.
Understanding the function of TAS2R20 can provide insights into taste perception mechanisms and may have implications for conditions related to taste disorders or eating behaviors. Research into TAS2R20 could also lead to new approaches for improving the palatability of bitter-tasting medications or developing novel taste-modifying agents for various applications.
Antibody Name:
TAS2R20 Antibody
Antibody SKU:
PACO03802
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human T2R49.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TAS2R20; TAS2R49; Taste receptor type 2 member 20; Taste receptor type 2 member 49; T2R49; Taste receptor type 2 member 56; T2R56
UniProt Protein Function:
TAS2R49: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: Receptor, GPCR; GPCR, T2R family; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 12p13.2Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; sensory perception of taste
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the taste receptor two family of class C G-protein coupled receptors. Receptors of this family have a short extracellular N-terminus, seven transmembrane helices, three extracellular loops and three intracellular loops, and an intracellular C-terminus. Members of this family are expressed in a subset of taste receptor cells, where they function in bitter taste reception, as well as in non-gustatory cells including those of the brain, reproductive organs, respiratory system, and gastrointestinal system. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2016]
