The TAS2R3 Antibody (PAC004505) is a polyclonal antibody designed for research involving TAS2R3, a G protein-coupled receptor involved in the perception of bitter compounds. The antibody, developed through immunization of rabbits, is highly specific to human TAS2R3 samples and has been validated for use in various applications, including Western blot and immunohistochemistry.TAS2R3 is a key player in the detection of bitter tastes, playing a crucial role in the human sense of taste and influencing food preferences and choices. Research involving TAS2R3 can provide insights into taste perception mechanisms, as well as potential implications for conditions such as obesity and eating disorders.
This antibody enables the detection and analysis of TAS2R3 protein expression in different cell types, making it a valuable tool for studies in taste perception, nutrition, and sensory science. Understanding the function and regulation of TAS2R3 can lead to advancements in the development of taste-modifying compounds and potential therapeutic interventions for taste-related disorders.
Antibody Name:
TAS2R3 Antibody
Antibody SKU:
PACO04505
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human T2R3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TAS2R3; Taste receptor type 2 member 3; T2R3
UniProt Protein Function:
TAS2R3: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: GPCR, T2R family; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: 7q31.3-q32Cellular Component: integral to membrane; plasma membraneMolecular Function: bitter taste receptor activity; taste receptor activityBiological Process: detection of chemical stimulus involved in sensory perception of bitter taste; sensory perception of taste; signal transduction
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless taste receptor genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]
