The TAS2R38 Antibody (CAB15087) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TAS2R38 protein, this antibody allows for the detection and analysis of TAS2R38 in various cell types, making it suitable for studies in taste perception and sensory science.TAS2R38 is a member of the TAS2R family of taste receptors, specifically responsible for detecting bitter tastes. Variations in the TAS2R38 gene have been linked to differences in bitter taste sensitivity, which can influence food preferences and dietary choices.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Rat samples.
Product Name:
TAS2R38 Antibody
SKU:
CAB15087
Size:
20μL, 100μL
Reactivity:
Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PTC, T2R38, T2R61, THIOT, TAS2R38
Positive Sample:
rat thymus
Cellular Localization:
Membrane, Multi-Pass Membrane Protein.
Calculated MW:
38kDa
Observed MW:
38kDa
This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).
Purification Method
Affinity purification
Gene ID
5726
RRID
AB_2761970
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat thymus, using TAS2R38 Rabbit pAb (CAB15087) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
