The TAS2R39 Polyclonal Antibody (PACO01574) is specifically designed for research involving TAS2R39, a taste receptor protein involved in bitter taste perception. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in various research applications, including Western blotting. By binding to the TAS2R39 protein, this antibody enables detection and analysis in different cell types, making it suitable for studies in sensory biology and taste perception.
TAS2R39 is a member of the taste receptor family, specifically involved in detecting bitter compounds in the environment. Understanding the function and regulation of TAS2R39 is important for research in taste perception, food preference, and dietary behavior. This antibody provides a valuable tool for studying the role of TAS2R39 in human physiology and taste perception, with potential implications for research in nutrition, sensory science, and related fields.
Antibody Name:
TAS2R39 Antibody
Antibody SKU:
PACO01574
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human T2R39.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TAS2R39; Taste receptor type 2 member 39; T2R39; Taste receptor type 2 member 57; T2R57
UniProt Protein Function:
TAS2R39: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, T2R family; Membrane protein, multi-passChromosomal Location of Human Ortholog: 7q34Cellular Component: plasma membrane; integral to membraneMolecular Function: bitter taste receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of bitter taste
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a bitter taste receptor that detects green tea catechins, soy isoflavones, and theaflavins. The encoded protein is gustducin-linked and may activate alpha gustducin. This gene is intronless. [provided by RefSeq, Dec 2015]
