The TBX2 Antibody (CAB10250) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in various research applications such as Western blot and immunohistochemistry.TBX2 is a transcription factor that is involved in the regulation of cell proliferation, differentiation, and apoptosis. Dysregulation of TBX2 has been linked to various diseases, including cancer and developmental disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
TBX2 Antibody
SKU:
CAB10250
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:
GSLS RSPF LGSA RPRL RFSP YQIP VTIP PSTS LLTT GLAS EGSK AAGG NSRE PSPL PELA LRKV GAPS RGAL SPSG SAKE AANE LQSI QRLV SGLE SQRA LSPG RESP K
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:1000 - 1:2000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
VETD, TBX2
Positive Sample:
SH-SY5Y, U-87MG, MCF7, Mouse ovary, Rat lung
Cellular Localization:
Nucleus.
Calculated MW:
75kDa
Observed MW:
75kDa
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.
Purification Method
Affinity purification
Gene ID
6909
RRID
AB_2757777
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using TBX2 Rabbit pAb (CAB10250) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
