The TEKT3 Polyclonal Antibody (PAC01510) is a versatile tool for researchers studying TEKT3, a protein involved in the formation of ciliary microtubules essential for cell motility. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TEKT3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for research in fields such as cell biology and developmental biology.
TEKT3 is a crucial component of the ciliary structure, playing a key role in the maintenance of ciliary function and cell movement. Its involvement in cilia formation and function makes it a valuable target for investigations into ciliopathies, developmental disorders, and diseases related to ciliary dysfunction. By studying the function of TEKT3, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.
Antibody Name:
TEKT3 Antibody (PACO15110)
Antibody SKU:
PACO15110
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human TEKT3
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15110(TEKT3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15110(TEKT3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. The exact function of this gene is not known. Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility.
Synonyms:
Tektin 3
UniProt Protein Function:
TEKT3: Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility. Belongs to the tektin family.Chromosomal Location of Human Ortholog: 17p12Cellular Component: acrosomal membrane; nucleusMolecular Function: protein bindingBiological Process: sperm motility
UniProt Protein Details:
NCBI Summary:
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
