The TEKT3 Polyclonal Antibody (PAC040990) is a valuable tool for researchers studying TEKT3, a protein involved in the formation of cilia and flagella. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the TEKT3 protein, this antibody allows for accurate detection and analysis in various cell types, making it an ideal choice for investigations in the fields of cell biology and developmental biology.
TEKT3 is a key player in the assembly and function of cilia and flagella, structures essential for cell motility and signal transduction. Understanding the role of TEKT3 is crucial for uncovering insights into developmental processes, genetic disorders, and diseases related to cilia dysfunction. Research involving TEKT3 may lead to advancements in therapies targeting cilia-related conditions, making this antibody a valuable asset for scientists working in these areas.
Immunohistochemistry of paraffin-embedded human liver tissue using PACO40990 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO40990 at dilution of 1:100.
Background:
Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility.
Synonyms:
Tektin-3, TEKT3
UniProt Protein Function:
TEKT3: Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for progressive sperm mobility. Belongs to the tektin family.Chromosomal Location of Human Ortholog: 17p12Cellular Component: acrosomal membrane; nucleusMolecular Function: protein bindingBiological Process: sperm motility
UniProt Protein Details:
NCBI Summary:
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
