The TFAP2B Antibody (CAB7935) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. It targets the TFAP2B protein, allowing for detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and genetic research.TFAP2B, also known as transcription factor AP-2 beta, plays a crucial role in gene regulation and cellular differentiation, making it a key player in processes such as embryonic development and tissue homeostasis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
TFAP2B Antibody
SKU:
CAB7935
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PDA2, AP-2B, AP2-B, AP-2beta, TFAP2B
Positive Sample:
SH-SY5Y, U-937(Negative control)
Cellular Localization:
Nucleus.
Calculated MW:
50kDa
Observed MW:
50kDa
This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
Purification Method
Affinity purification
Gene ID
7021
RRID
AB_2772571
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using TFAP2B Rabbit pAb (CAB7935) at 1:900 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
