The TGM7 Polyclonal Antibody (PAC020750) is a valuable tool for researchers studying transglutaminase 7 (TGM7), a protein involved in cellular processes such as apoptosis and differentiation. This antibody, generated in rabbits, exhibits high sensitivity and specificity when binding to TGM7 in human samples, making it ideal for use in Western blot applications.TGM7 is known for its role in regulating cellular functions through protein crosslinking and has been implicated in various diseases, including cancer and neurodegenerative disorders.
By targeting TGM7 with this antibody, researchers can gain valuable insights into the protein's function and its potential implications in disease progression.With its ability to detect TGM7 in different cell types, the TGM7 Polyclonal Antibody is a valuable tool for studies in molecular biology, cancer research, and neurobiology. By understanding the mechanisms by which TGM7 operates, researchers can pave the way for potential therapeutic interventions targeting this protein in disease settings.
Antibody Name:
TGM7 Antibody (PACO20750)
Antibody SKU:
PACO20750
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human TGM7
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO20750(TGM7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO20750(TGM7 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
Transglutaminases (TGM; EC 2.3.2.13) are a family of structurally and functionally related enzymes that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. For additional background information on transglutaminases, see TGM1 (MIM 190195).
Synonyms:
transglutaminase 7
UniProt Protein Function:
TGM7: an enzyme of the transglutaminase family that catalyzes the crosslinking of proteins and the conjugation of polyamines to proteins. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Protein type: EC 2.3.2.13; TransferaseChromosomal Location of Human Ortholog: 15q15.2
