Description
THBS2 Monoclonal Antibody (CAB23296)
The THBS2 Monoclonal Antibody is a vital tool for researchers studying Thrombospondin 2 (THBS2), a glycoprotein involved in cell-to-cell and cell-to-matrix interactions in the extracellular matrix. The antibody, produced from mouse hybridoma cells, demonstrates high specificity and sensitivity in detecting THBS2 in various biological samples. Validated for use in immunofluorescence and immunohistochemistry applications, this antibody enables precise localization and visualization of THBS2, making it ideal for investigations in tissue development, wound healing, and cancer progression.
THBS2 is known to regulate cell adhesion, migration, and proliferation, influencing processes such as angiogenesis, tissue remodeling, and inflammation. Its dysregulation has been linked to various pathologies, including cancer metastasis, fibrosis, and cardiovascular diseases. By targeting THBS2, researchers can gain insights into its role in disease progression and potentially identify new therapeutic strategies for intervention. This monoclonal antibody serves as a valuable tool in advancing our understanding of THBS2 function and its implications in health and disease.
| Product Name: | THBS2 Monoclonal Antibody |
| Product Code: | CAB23296 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60179 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | U-87 MG |
The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration.
| Immunogen: | Recombinant protein of human THBS2. |
| Sequence: | MVWRL VLLAL WVWPS TQAGH QDKDT TFDLF SISNI NRKTI GAKQF RGPDP GVPAY RFVRF DYIPP VNADD LSKIT KIMRQ KEGFF LTAQL KQDGK SRGTL LALEG PGLSQ RQFEI VSNGP ADTLD LTYWI DGTRH VVSLE DVGLA DSQWK NVTVQ VAGET YSLHV GCDLI DSFAL DEPFY EHLQA EKSRM YVAKG SARES HFRGL LQNVH LVFEN SVEDI LSKKG CQQGQ GAEIN AISEN TETLR LGPHV TTEYV GPSSE RRPEV CERSC EELGN MVQEL SGLHV LVNQL SENLK RVSND NQFLW ELIGG PPKTR NMSAC WQDGR FFAEN ETWVV DSCTT CTCKK FKTIC HQITC PPATC ASPSF VEGEC CPSCL HSVDG EEGWS PWAEW TQCSV TCGSG TQQRG RSCDV TSNTC LGPSI QTRAC SLSKC DTRIR QDGGW SHWSP WSSCS VTCGV GNITR IRLCN SPVPQ MGGKN CKGSG RETKA CQGAP CPIDG RWSPW SPWSA CTVTC AGGIR ERTRV CNSPE PQYGG KACVG DVQER QMCNK RSCPV DGCLS NPCFP GAQCS SFPDG SWSCG SCPVG FLGNG THCED LDECA LVPDI CFSTS KVPRC VNTQP GFHCL PCPPR YRGNQ PVGVG LEAAK TEKQV CEPEN PCKDK THNCH KHAEC IYLGH FSDPM YKCEC QTGYA GDGLI CGEDS DLDGW PNLNL VCATN ATYHC IKDNC PHLPN SGQED FDKDG IGDAC DDDDD NDGVT DEKDN CQLLF NPRQA DYDKD EVGDR CDNCP YVHNP AQIDT DNNGE GDACS VDIDG DDVFN ERDNC PYVYN TDQRD TDGDG VGDHC DNCPL VHNPD QTDVD NDLVG DQCDN NEDID DDGHQ NNQDN CPYIS NANQA DHDRD GQGDA CDPDD DNDGV PDDRD NCRLV FNPDQ EDLDG DGRGD ICKDD FDNDN IPDID DVCPE NNAIS ETDFR NFQMV PLDPK GTTQI DPNWV IRHQG KELVQ TANSD PGIAV GFDEF GSVDF SGTFY VNTDR DDDYA GFVFG YQSSS RFYVV MWKQV TQTYW EDQPT RAYGY SGVSL KVVNS TTGTG EHLRN ALWHT GNTPG QVRTL WHDPR NIGWK DYTAY RWHLT HRPKT GYIRV LVHEG KQVMA DSGPI YDQTY AGGRL GLFVF SQEMV YFSDL KYECR DI |
| Synonyms: | TSP2 |
| Calculated MW: | 130kDa |
| Observed MW: | 210kDa |
