The TMPRSS11E Polyclonal Antibody (PAC017281) is a valuable tool for researchers studying TMPRSS11E, a cell surface protein involved in various biological processes. This polyclonal antibody, generated in rabbits, shows high reactivity towards human samples and has been validated for use in Western blot applications. By binding specifically to the TMPRSS11E protein, this antibody allows for the detection and analysis of TMPRSS11E in different cell types, making it an ideal choice for studies in immunology, cancer research, and beyond.
TMPRSS11E, also known as a type II transmembrane serine protease, has been implicated in processes such as cell signaling, protein processing, and tissue remodeling. Its role in these pathways makes it a promising target for research into diseases such as cancer, inflammatory disorders, and infectious diseases. Understanding the function and regulation of TMPRSS11E is essential for the development of novel therapeutic strategies that target this protein and its associated pathways.
Antibody Name:
TMPRSS11E Antibody (PACO17281)
Antibody SKU:
PACO17281
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:30-1:150
Species Reactivity:
Human
Immunogen:
Fusion protein of human TMPRSS11E
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17281(TMPRSS11E Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17281(TMPRSS11E Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position (By similarity).
Synonyms:
transmembrane protease, serine 11E
UniProt Protein Function:
TMPRSS11E: Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position. Belongs to the peptidase S1 family.Protein type: Membrane protein, integral; Protease; EC 3.4.21.-Chromosomal Location of Human Ortholog: 4q13.2Cellular Component: integral to plasma membraneMolecular Function: serine-type peptidase activityBiological Process: cognition; proteolysis
