Description
TMSB10 Antibody (PACO18475)
The TMSB10 Monoclonal Antibody (PAC018475) is a specialized tool for researchers studying TMSB10, a key protein involved in cell motility and invasion. This monoclonal antibody, produced in mice, offers high specificity and sensitivity in detecting TMSB10 in a variety of cell types. Validated for use in immunofluorescence and flow cytometry, it provides valuable insights into the function and localization of TMSB10 within cells.TMSB10, also known as thymosin beta-10, is a widely studied protein with implications in cell migration, wound healing, and cancer metastasis.
By targeting TMSB10, researchers can explore its role in various physiological and pathological processes, making it a valuable tool in cancer research, developmental biology, and regenerative medicine. Understanding the functions of TMSB10 is essential for unlocking its therapeutic potential in treating diseases associated with cell mobility and tissue remodeling.
| Antibody Name: | TMSB10 Antibody (PACO18475) |
| Antibody SKU: | PACO18475 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:3000-1:10000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human TMSB10 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO18475(TMSB10 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18475(TMSB10 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This protein plays an important role in the organization of the cytoskeleton. It binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Experiment indicate that the expression decrease dramatically after birth. It expresses high levels in human fetal brain. |
| Synonyms: | thymosin β 10 |
| UniProt Protein Function: | TMSB10: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2p11.2 Cellular Component: cytoskeleton; cytoplasm Molecular Function:actin monomer binding Biological Process: sequestering of actin monomers; actin filament organization |
| UniProt Code: | P63313 |
| NCBI GenInfo Identifier: | 54039778 |
| NCBI Gene ID: | 9168 |
| NCBI Accession: | P63313.2 |
| UniProt Secondary Accession: | P63313,P13472, Q596K9, |
| UniProt Related Accession: | P63313 |
| Molecular Weight: | 5,026 Da |
| NCBI Full Name: | Thymosin beta-10 |
| NCBI Synonym Full Names: | thymosin beta 10 |
| NCBI Official Symbol: | TMSB10Â Â |
| NCBI Official Synonym Symbols: | TB10; MIG12Â Â |
| NCBI Protein Information: | thymosin beta-10; migration-inducing gene 12; migration-inducing protein 12 |
| UniProt Protein Name: | Thymosin beta-10 |
| Protein Family: | Thymosin |
| UniProt Gene Name: | TMSB10Â Â |
| UniProt Entry Name: | TYB10_HUMAN |
