Description
TMSB10 Antibody (PACO20643)
The TMSB10 Polyclonal Antibody (PAC020643) is a valuable tool for researchers studying the TMSB10 protein, a member of the beta-thymosin family involved in actin sequestration and cell motility. This antibody, produced in rabbits, exhibits high reactivity with human samples, making it an ideal choice for various research applications, including Western blotting.By specifically binding to TMSB10, this antibody enables the accurate detection and analysis of TMSB10 expression in different cell types, providing insights into its role in cellular processes and potential implications for diseases such as cancer and neurological disorders.
The TMSB10 protein's function in actin dynamics and cell movement highlights its importance in various physiological and pathological conditions, making it a valuable target for further investigation in the fields of cell biology and disease research.
| Antibody Name: | TMSB10 Antibody (PACO20643) |
| Antibody SKU: | PACO20643 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:30-1:150 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human TMSB10 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20643(TMSB10 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20643(TMSB10 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Thymosin beta-10 plays an important role in the organization of the cytoskeleton. Thymosin beta-10 binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. The expression of thymosin beta-10 dramatically decreases after birth. |
| Synonyms: | thymosin β 10 |
| UniProt Protein Function: | TMSB10: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2p11.2 Cellular Component: cytoskeleton; cytoplasm Molecular Function:actin monomer binding Biological Process: sequestering of actin monomers; actin filament organization |
| UniProt Code: | P63313 |
| NCBI GenInfo Identifier: | 54039778 |
| NCBI Gene ID: | 9168 |
| NCBI Accession: | P63313.2 |
| UniProt Secondary Accession: | P63313,P13472, Q596K9, |
| UniProt Related Accession: | P63313 |
| Molecular Weight: | 5,026 Da |
| NCBI Full Name: | Thymosin beta-10 |
| NCBI Synonym Full Names: | thymosin beta 10 |
| NCBI Official Symbol: | TMSB10Â Â |
| NCBI Official Synonym Symbols: | TB10; MIG12Â Â |
| NCBI Protein Information: | thymosin beta-10; migration-inducing gene 12; migration-inducing protein 12 |
| UniProt Protein Name: | Thymosin beta-10 |
| Protein Family: | Thymosin |
| UniProt Gene Name: | TMSB10Â Â |
| UniProt Entry Name: | TYB10_HUMAN |
