The TMX4 Antibody (PACO12818) is a valuable tool for researchers studying the TMX4 protein, implicated in a variety of cellular processes. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.TMX4, a member of the thioredoxin superfamily, is involved in protein folding and redox regulation within the endoplasmic reticulum. Its functions in maintaining protein homeostasis and cellular integrity make it a key player in processes such as oxidative stress response and protein quality control.
By specifically binding to the TMX4 protein, this antibody enables precise detection and analysis in various cell types, providing insights into its role in cellular physiology and potential implications in diseases such as neurodegenerative disorders or cancer. Researchers interested in unraveling the complex functions of TMX4 will find this antibody to be a valuable asset in their studies.
thioredoxin-related transmembrane protein 4;TMX4;DJ971N18.2;KIAA1162;PDIA14;TXNDC13 ;
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The encoded protein has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017]
