The TNF RII/TNFRSF1B/CD120b Polyclonal Antibody (CAB24513) is a high-quality antibody developed for reliable detection and analysis of target proteins. This cell surface receptor is involved in mediating the biological effects of tumor necrosis factor (TNF), a key cytokine in the immune response. The antibody is raised in rabbits and is highly specific for human samples, making it ideal for use in Western blot applications.TNF RII plays a crucial role in regulating immune responses, inflammation, and cell death pathways. It is a target of interest in studies related to inflammatory diseases, autoimmune disorders, and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
TNF RII/TNFRSF1B/CD120b Polyclonal Antibody
SKU:
CAB24513
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including negative regulation of extracellular matrix constituent secretion; regulation of nervous system development; and semi-lunar valve development. Acts upstream of or within several processes, including RNA destabilization; apoptotic signaling pathway; and negative regulation of inflammatory response. Located in membrane raft. Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; genitourinary system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Parkinsonism; acne; bone disease (multiple); glomerulonephritis (multiple); and lung disease (multiple). Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B).
Purification Method
Affinity purification
Gene ID
21938
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from L929 cells using TNF RII/TNFRSF1B/CD120b Rabbit pAb (CAB24513) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
