The TNIP2 Polyclonal Antibody (CAB4962) is a valuable tool for researchers studying TNIP2, a protein involved in immune regulation and inflammatory pathways. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for Western blot applications. By binding to TNIP2, this antibody enables the detection and analysis of the protein in various cell types, making it ideal for studies in immunology, inflammation, and autoimmune diseases.
TNIP2, also known as ABIN-2, is a crucial regulator of NF-κB signaling, a pathway involved in the immune response and inflammation. Its role in modulating immune activation and cytokine production makes it a key target for research into inflammatory conditions and autoimmune disorders. Understanding the function of TNIP2 is essential for developing therapies that regulate immune responses and treat these diseases effectively.
Product Name:
TNIP2 Rabbit Polyclonal Antibody
SKU:
CAB4962
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-429 of human TNIP2 (NP_077285.3).
This gene encodes a protein which acts as an inhibitor of NFkappaB activation. The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types. It may be involved in apoptosis of endothelial cells. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on the X chromosome.
Purification Method:
Affinity purification
Gene ID:
79155
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse pancreas, using TNIP2 Rabbit pAb (CAB4962) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
