Description
TPPP2 Antibody (PACO30734)
The TPPP2 Polyclonal Antibody (PAC030734) is a valuable tool for researchers studying TPPP2, a protein involved in microtubule stabilization and neurite outgrowth. Raised in rabbits, this antibody offers high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to TPPP2, researchers can accurately detect and analyze this protein in various cell types, making it ideal for studies in neuroscience and neurodegenerative diseases.TPPP2, also known as tubulin polymerization-promoting protein family member 2, plays a crucial role in maintaining the stability of microtubules in neurons, which is essential for proper neurite outgrowth and neuronal function.
Dysregulation of TPPP2 has been linked to neurodegenerative disorders such as Alzheimer's and Parkinson's disease, making it a promising target for therapeutic research. Understanding the function of TPPP2 is integral to developing novel treatments for these debilitating conditions.
| Antibody Name: | TPPP2 Antibody (PACO30734) |
| Antibody SKU: | PACO30734 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Tubulin polymerization-promoting protein family member 2 protein (1-170AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: TPPP2 antibody at 8µg/ml + HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 19 kDa Observed band size: 19 kDa . |
 | Immunofluorescent analysis of MCF-7 cells using PACO30734 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO30734 at dilution of 1:100. |
| Background: | May bind tubulin but has no microtubule bundling activity. |
| Synonyms: | Tubulin polymerization-promoting protein family member 2 (Protein p25-beta) (TPPP/p18), TPPP2, C14orf8 |
| UniProt Protein Function: | TPPP2: May bind tubulin but has no microtubule bundling activity. Belongs to the TPPP family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 14q11.2Cellular Component: cytoplasm |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P59282 |
| NCBI GenInfo Identifier: | 226491350 |
| NCBI Gene ID: | 122664 |
| NCBI Accession: | NP_776245.2 |
| UniProt Secondary Accession: | P59282,Q2VYF3 |
| UniProt Related Accession: | P59282 |
| Molecular Weight: | 18,503 Da |
| NCBI Full Name: | tubulin polymerization-promoting protein family member 2 |
| NCBI Synonym Full Names: | tubulin polymerization-promoting protein family member 2 |
| NCBI Official Symbol: | TPPP2Â Â |
| NCBI Official Synonym Symbols: | P18; CT152; C14orf8; p25beta  |
| NCBI Protein Information: | tubulin polymerization-promoting protein family member 2 |
| UniProt Protein Name: | Tubulin polymerization-promoting protein family member 2 |
| UniProt Synonym Protein Names: | Protein p25-beta; TPPP/p18 |
| Protein Family: | Tubulin polymerization-promoting protein family |
| UniProt Gene Name: | TPPP2Â Â |
| UniProt Entry Name: | TPPP2_HUMAN |
| Antibodies |
| TPPP2 Antibody (PACO12871) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
