Tpsb2 Antibody (PACO30747)
- SKU:
- PACO30747
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Tpsb2 Antibody (PACO30747)
The TPSB2 Polyclonal Antibody (PACO30747) is a valuable tool for researchers studying TPSB2, a serine protease involved in various physiological processes, including inflammation and coagulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human TPSB2, making it an excellent choice for Western blot applications.TPSB2, also known as tryptase beta-2, is predominantly expressed in mast cells and has been implicated in various disease states, including asthma, allergies, and inflammatory conditions.
By targeting TPSB2 with this antibody, researchers can gain insights into its function and potentially develop novel therapeutic strategies for these conditions.With its ability to detect TPSB2 in different cell types, the PACO30747 antibody is a versatile tool for research in immunology, allergy, and inflammation. By elucidating the role of TPSB2 in disease pathogenesis, this antibody has the potential to advance our understanding of these conditions and identify new targets for therapeutic intervention.
| Antibody Name: | Tpsb2 Antibody (PACO30747) |
| Antibody SKU: | PACO30747 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Mouse, Rat |
| Immunogen: | Recombinant Mouse Tryptase beta-2 protein (32-276AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Tpsb2 antibody at 2µg/ml Lane 1: Mouse heart tissue Lane 2: Rat heart tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 31, 26 kDa Observed band size: 31 kDa . |
| Background: | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Required to efficiently combat K.pneumoniae infection. |
| Synonyms: | Tryptase beta-2 (Tryptase-2) (EC 3.4.21.59) (Mast cell protease 6) (mMCP-6), Tpsb2, Mcpt6 |
| UniProt Protein Function: | TPSB2: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Has an immunoprotective role during bacterial infection. Required to efficiently combat K.pneumoniae infection. Belongs to the peptidase S1 family. Tryptase subfamily. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Protease; EC 3.4.21.59; Secreted Cellular Component: extracellular matrix; extracellular region; extracellular space Molecular Function:heparin binding; hydrolase activity; peptidase activity; protein binding; serine-type endopeptidase activity; serine-type peptidase activity Biological Process: inflammatory response; proteolysis |
| UniProt Code: | P21845 |
| NCBI GenInfo Identifier: | 126839 |
| NCBI Gene ID: | 17229 |
| NCBI Accession: | P21845.2 |
| UniProt Secondary Accession: | P21845,Q61962, |
| UniProt Related Accession: | P21845 |
| Molecular Weight: | 25,829 Da |
| NCBI Full Name: | Tryptase beta-2 |
| NCBI Synonym Full Names: | tryptase beta 2 |
| NCBI Official Symbol: | Tpsb2 |
| NCBI Official Synonym Symbols: | Mcp6; Mcp-6; Mcpt6; MMCP-6; AV011504 |
| NCBI Protein Information: | tryptase beta-2 |
| UniProt Protein Name: | Tryptase beta-2 |
| UniProt Synonym Protein Names: | Mast cell protease 6; mMCP-6 |
| Protein Family: | Tryptase |
| UniProt Gene Name: | Tpsb2 |
| UniProt Entry Name: | TRYB2_MOUSE |
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