The TRbeta1/THRB Monoclonal Antibody (CAB22560) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody specifically targets the THRB protein, enabling accurate detection and analysis in various biological samples.Raised and purified in a controlled environment, this antibody offers high specificity and sensitivity, making it a reliable tool for studying the role of THRB in various cellular processes. It is validated for use in Western blot applications, allowing researchers to explore the expression levels and localization of THRB in different cell types.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
TRbeta1/THRB Monoclonal Antibody
SKU:
CAB22560
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC56361
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
Purification Method
Affinity purification
Gene ID
7068
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TRβ1/THRB Rabbit mAb (CAB22560) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
