Description
TRA2A Antibody (PACO01647)
The TRA2A Monoclonal Antibody (PACO01647) is a powerful tool for researchers studying TRA2A, an important splicing factor involved in regulating alternative splicing of pre-mRNA. This antibody, produced through monoclonal technology, specifically targets TRA2A and is highly reactive with human samples. It has been validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry.TRA2A is known for its role in modulating the splicing patterns of specific genes, influencing protein diversity and function. Dysregulation of alternative splicing has been linked to various diseases, including cancer and neurological disorders.
As such, TRA2A is a key target for research in understanding disease mechanisms and developing potential therapeutic interventions.By utilizing the TRA2A Monoclonal Antibody, researchers can effectively study the expression and localization of TRA2A in different cell types and tissues, gaining valuable insights into its function in gene regulation and disease pathogenesis. This antibody is a valuable asset for scientists investigating the complex mechanisms of RNA splicing and its implications in health and disease.
| Antibody Name: | TRA2A Antibody |
| Antibody SKU: | PACO01647 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the C-terminal region of human Tra-2alpha. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | TRA2A; Transformer-2 protein homolog alpha; TRA-2 alpha; TRA2-alpha; Transformer-2 protein homolog A |
| UniProt Protein Function: | TRA2A: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Belongs to the splicing factor SR family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA processing; RNA splicing; RNA-binding Chromosomal Location of Human Ortholog: 7p15.3 Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus Biological Process: nuclear mRNA splicing, via spliceosome |
| NCBI Summary: | This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q13595 |
| NCBI GenInfo Identifier: | 4033480 |
| NCBI Gene ID: | 29896 |
| NCBI Accession: | Q13595.1 |
| UniProt Secondary Accession: | Q13595,B4DQI6, B4DUA9, E9PD75, |
| UniProt Related Accession: | Q13595 |
| Molecular Weight: | 20,590 Da |
| NCBI Full Name: | Transformer-2 protein homolog alpha |
| NCBI Synonym Full Names: | transformer 2 alpha homolog |
| NCBI Official Symbol: | TRA2AÂ Â |
| NCBI Official Synonym Symbols: | AWMS1; HSU53209Â Â |
| NCBI Protein Information: | transformer-2 protein homolog alpha |
| UniProt Protein Name: | Transformer-2 protein homolog alpha |
| UniProt Synonym Protein Names: | Transformer-2 protein homolog A |
| Protein Family: | Transformer-2 protein |
| UniProt Gene Name: | TRA2AÂ Â |
| UniProt Entry Name: | TRA2A_HUMAN |
