Description
TRA2A Antibody (PACO12880)
The TRA2A Polyclonal Antibody (PAC012880) is a valuable research tool for studying TRA2A, a splicing factor involved in RNA processing. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the TRA2A protein, researchers can detect and analyze its expression in various cell types, making it an ideal tool for investigations in molecular biology and gene regulation.TRA2A is known for its role in alternative splicing, a process critical for generating protein diversity and regulating gene expression.
Dysregulation of splicing factors like TRA2A can lead to disease, making them important targets for therapeutic research. By understanding the function of TRA2A, researchers can gain insights into diseases such as cancer and neurological disorders, potentially leading to the development of innovative treatments targeting RNA processing mechanisms.
| Antibody Name: | TRA2A Antibody (PACO12880) |
| Antibody SKU: | PACO12880 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human TRA2A |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | transformer 2 α homolog (Drosophila);TRA2A;HSU53209 ; |
| UniProt Protein Function: | TRA2A: Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Belongs to the splicing factor SR family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA processing; RNA splicing; RNA-binding Chromosomal Location of Human Ortholog: 7p15.3 Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus Biological Process: nuclear mRNA splicing, via spliceosome |
| NCBI Summary: | This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q13595 |
| NCBI GenInfo Identifier: | 4033480 |
| NCBI Gene ID: | 29896 |
| NCBI Accession: | Q13595.1 |
| UniProt Secondary Accession: | Q13595,B4DQI6, B4DUA9, E9PD75, |
| UniProt Related Accession: | Q13595 |
| Molecular Weight: | 20,590 Da |
| NCBI Full Name: | Transformer-2 protein homolog alpha |
| NCBI Synonym Full Names: | transformer 2 alpha homolog |
| NCBI Official Symbol: | TRA2AÂ Â |
| NCBI Official Synonym Symbols: | AWMS1; HSU53209Â Â |
| NCBI Protein Information: | transformer-2 protein homolog alpha |
| UniProt Protein Name: | Transformer-2 protein homolog alpha |
| UniProt Synonym Protein Names: | Transformer-2 protein homolog A |
| Protein Family: | Transformer-2 protein |
| UniProt Gene Name: | TRA2AÂ Â |
| UniProt Entry Name: | TRA2A_HUMAN |
