The Trak2 Polyclonal Antibody (PACO5095) is a valuable tool for researchers studying the Trak2 protein, a crucial regulator of mitochondrial dynamics and cell division. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to Trak2, this antibody enables accurate detection and analysis of Trak2 expression in various cell types, making it an ideal choice for studies in cell biology and cancer research.Trak2, also known as trafficking kinesin-binding protein 2, plays a key role in coordinating the movement of mitochondria within cells, which is essential for maintaining cellular health and function.
Dysregulation of Trak2 has been implicated in various diseases, including cancer and neurodegenerative disorders. Therefore, understanding the functions and regulation of Trak2 is crucial for developing targeted therapies that aim to restore mitochondrial dynamics and cellular homeostasis in these pathological conditions.Overall, the Trak2 Polyclonal Antibody (PACO5095) offers researchers a reliable tool for investigating the role of Trak2 in cellular processes and disease pathogenesis, ultimately paving the way for the development of novel therapeutic strategies targeting this important protein.
Antibody Name:
TRAK2 Antibody (PACO05095)
Antibody SKU:
PACO05095
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:10000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human GRIF-1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
TRAK2; ALS2CR3; KIAA0549; Trafficking kinesin-binding protein 2; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein
UniProt Protein Function:
TRAK2: an O-glycosylated protein that is widely expressed and that interacts with kinesin and O-GlcNAc transferase (OGT). Interacts with mitochondrial rho GTPase 2 (MIRO-2) forming a link between mitochondria and the trafficking apparatus of the microtubules.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2q33Cellular Component: cytoplasm; early endosome; mitochondrion; nucleus; plasma membraneMolecular Function: enzyme binding; GABA receptor binding; protein binding; receptor bindingBiological Process: protein amino acid O-linked glycosylation; protein targeting; regulation of transcription from RNA polymerase II promoter
