The TSGA10 Polyclonal Antibody (PAC040518) is a valuable tool for researchers studying TSGA10, a protein involved in testis-specific functions and potentially implicated in cancer development. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TSGA10 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it a versatile tool for studies in reproductive biology and cancer research.TSGA10, also known as Testis Specific Gene Antigen 10, is primarily expressed in the testis and has been found to play a role in spermatogenesis and sperm function.
Additionally, emerging research suggests that TSGA10 may be involved in cancer progression, making it an intriguing target for further investigation. Understanding the function and regulation of TSGA10 is essential for gaining insight into its potential roles in both normal physiological processes and disease states, paving the way for the development of novel therapeutic approaches in the future.
Western blot. All lanes: TSGA10 antibody at 1.5µg/ml + U251 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 82, 35 kDa. Observed band size: 82 kDa.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO40518 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO40518 at dilution of 1:100.
Background:
May play a role in the sperm tail fibrous sheath, a major sperm tail structure.
Synonyms:
Testis-specific gene 10 protein (Testis development protein NYD-SP7), TSGA10, CEP4L
UniProt Protein Function:
TSGA10: May play a role in the sperm tail fibrous sheath, a major sperm tail structure. Belongs to the CEP135/TSGA10 family.Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: 2q11.2Molecular Function: protein bindingBiological Process: spermatogenesis
