The TSPAN13 Polyclonal Antibody (PAC020706) is a essential tool for researchers studying TSPAN13, a cell surface protein involved in various cellular processes. This antibody, developed using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the TSPAN13 protein, this antibody enables precise detection and analysis in different cell types, making it ideal for studies in cell biology and cancer research.TSPAN13, also referred to as a transmembrane 4 superfamily member 13, plays a crucial role in cell adhesion, migration, and signal transduction pathways.
Its involvement in these vital cellular functions highlights the importance of investigating its role in normal physiology and disease states. Understanding the functions and mechanisms of TSPAN13 can provide insights into various pathological conditions, including cancer metastasis and developmental disorders. This antibody serves as a valuable tool for researchers aiming to elucidate the molecular mechanisms underlying TSPAN13-mediated cellular processes.
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20706(TSPAN13 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 12%SDS-PAGE, Lysate: 40 µg, Lane: Human fetal brain tissue, Primary antibody: PACO20706(TSPAN13 Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20706(TSPAN13 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
Synonyms:
tetraspanin 13
UniProt Protein Function:
TSPAN13: a multi-pass membrane protein. Member of the transmembrane 4 superfamily, also known as the tetraspanin family. These proteins apparently mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. and RefSeqProtein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 7p21.1Cellular Component: membrane; integral to plasma membrane
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
